Crustacean Restaurant
Mixed reviews about this Vietnamese restaurant, so make your own decision. However, the roast crab has consistently garnered good reviews.
Frascati
A pan-European that is somewhat fancy but still relaxed and features local food.
Front Room Pizza
Arguably the best pizza in Nob Hill.
Harris' Restaurant
Excellent steak house; luxurious dining plush seats, table cloths, brass chandeliers, etc..
Nara Sushi
Popular with locals that rave about the freshness of the sushi here. Solid sushi at good prices, and large quantities too.
Nob Hill Cafe
A north Italian bistro that serves lunch, dinner and a Sunday brunch.
Okoze Sushi
A good sushi restaurant very near the cable car lines on Hyde Street. There is typically no need for a reservation.
Ristorante Milano
Pleasant Italian restaurant.
Zarzuela
Spanish tapas, hor d'oeuvres and appetizers.
Big Four Restaurant
In the Huntington Hotel.
There are many great options in these two neighborhoods -- lots of smallish, cozy eateries. Frequently the nicer restaurants require reservations.
Za Gourmet Pizza
A good, cheap pizza-by-the-slice restaurant that is open relatively late.